Product Description

HLX1 (Q338) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS2658-50, BS2658-100

Sizes: 50µl, 100µl

Swiss-Prot: Q14774

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

Background: HLX1 (homeobox protein HB24) is a 488 amino acid protein encoded by the human gene HLX1. HLX1 belongs to the H2.0 homeobox family and contains one homeobox DNA-binding domain. HLX1 is considered a diverged human homeodomain-containing protein known to be expressed in hematopoietic progenitors and activated lymphocytes. HLX1 is a transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression. It is also involved in embryogenesis and hematopoiesis. Overexpression of HLX1 will cause a marked increase in activated T cells/thymocytes and interleukin-2 receptor expression. Overexpression will also impair the normal development of CD4+ T cells and will prevent the thymus from undergoing normal involution.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: HLX1 (Q338) polyclonal antibody detects endogenous levels of HLX1 protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of HLX1 (Q338) polyclonal antibody at 1:1000 dilution Lane 1: JURKAT whole cell lysate (37ug)
Lane 2: THP-1 whole cell lysate (37ug)
Lane 3: The peripheral blood cell lysate of Rat (36ug) Lane 4: The peripheral blood cell lysate of Mouse (36ug) , Immunohistochemistry (IHC) analyzes of HoxD12 (E230) pAb in paraffin-embedded human brain tissue.

Bioworld Molecular Weight: ~ 75 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: H2.0 like homeobox 1 Drosophila; H2.0-like homeobox protein; HLX; HLX; Homeobox protein HB24; Homeobox protein HLX1;

Immunogen: Synthetic peptide, corresponding to amino acids 303-360 of Human HLX1.

Conjugate: Unconjugated

Modification: Unmodified