HMG-2 rabbit pAb - ES2540

HMG-2 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES2540-50, ES2540-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V (D)J recombination. [provided by RefSeq, Jul 2008],

Alternate Name: HMGB2; HMG2; High mobility group protein B2; High mobility group protein 2; HMG-2

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human HMGB2. AA range:131-180

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 27kD

Human Gene ID: 3148

Human SWISS Prot NO: P26583

Subcellular Location: Nucleus. Chromosome. Cytoplasm. Secreted. In basal state predominantly nuclear.

Research Use Only