Product Description

HMGA2 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-67520-60, E-AB-67520-120, E-AB-67520-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: HMGA2

Target Synonym: HMGA2; BABL; HMGI-C; HMGIC; LIPO; STQTL9

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Metabolism, Developmental biology, Neuroscience, Stem cells

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P52926

Background: This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Concentration: 1mg/mL

Immunogen: A synthetic peptide of human HMGA2

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 9kDa/10kDa/11kDa

Observed MW: 13kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only