Product Description

HMOX1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS3978-50, BS3978-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Swiss-Prot: P09601

Host: Rabbit

Reactivity: Human, Rat, Mouse

Applications: WB,

All Applications: WB: 1:1000~1:2000

Background: Heme oxygenase (HO) is the rate-limiting enzyme in the catabolism of heme that results in the release of carbon monoxide, iron, and biliverdin. The products of this enzymatic reaction play important biological roles in antioxidant, anti-inflammatory, and cytoprotective functions. HO comprises two isozymes, including the constitutively expressed HO-2 isozyme and the inducible HO-1 isozyme. Inducible HO-1 is expressed as an adaptive response to several stimuli, including heme, metals, and hormones. The induction of HO-1 has been implicated in numerous disease states, such as transplant rejection, hypertension, atherosclerosis, Alzheimer's disease, endotoxic shock, diabetes, inflammation, and neurological disorders.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: HMOX1 polyclonal antibody detects endogenous levels of HMOX1 protein.

Bioworld Molecular Weight: ~ 32 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of HMOX1 polyclonal antibody at 1:1000 dilution
Lane 1: HepG2 whole cell lysate (30ug)
Lane 2: A549 whole cell lysate (30ug)
Lane 3: A2780 whole cell lysate (30ug)
Lane 4: The Spleen tissue lysate of Mouse (30ug)
Lane 5: PMVEC whole cell lysate (30ug)

Alternative Name: Heme oxygenase 1; HO-1; Heme oxygenase 1 soluble form; HMOX1; HO; HO1

Immunogen: Recombinant protein of human HMOX1.

Conjugate: Unconjugated

Modification: Unmodified