hnRNP K (phospho Ser284) Polyclonal Antibody - RA26018

hnRNP K (phospho Ser284) Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA26018-50, RA26018-100

Citations, Manuals and MSDS Available upon request.

Background: heterogeneous nuclear ribonucleoprotein K (HNRNPK) Homo sapiens This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs) . The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA) . These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct among other hnRNP proteins in its binding preference; it binds tenaciously to poly (C) . This protein is also thought to have a role during cell cycle progession. Several alternatively spliced transcript variants have

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Alternative Names: HNRNPK; HNRPK; Heterogeneous nuclear ribonucleoprotein K; hnRNP K; Transformation up-regulated nuclear protein; TUNP

Applications: WB; IHC-p; IF (paraffin section) ; ELISA

Species Cross-Reactivity: Human; Mouse; Rat; Monkey

GeneID (Human): 3190

Protein MW (KDa): 51

SWISS: P61978

Source: Rabbit

Research Use Only