hnRNP U Mouse Monoclonal Antibody - RA11423

hnRNP U Mouse Monoclonal Antibody

Size: 50μL, 100μL

Catalogue Numbers: RA11423-50, RA11423-100

Citations, Manuals and MSDS Available upon request.

Background: heterogeneous nuclear ribonucleoprotein U (HNRNPU) Homo sapiens This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs) . The hnRNPs are RNA binding proteins and they form complexes with heterogeneous nuclear RNA (hnRNA) . These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene contains a RNA binding domain and scaffold-associated region (SAR) -specific bipartite DNA-binding domain. This protein is also thought to be involved in the packaging of hnRNA into large ribonucleoprotein complexes. During apoptosis, this protein is cleaved in a caspase-dependent way. Cleavage occurs at the

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Applications: WB

Species Cross-Reactivity: Human

GeneID (Human): 3192

Protein MW (KDa): 110

SWISS: Q00839

Source: Mouse

Research Use Only