hnRNP UL2 Polyclonal Antibody-BS62389

hnRNP UL2 Polyclonal Antibody

Catalogue Numbers: BS62389-50, BS62389-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.

Swiss-Prot: Q1KMD3

Host: Rabbit

Reactivity: Human, Rat, Mouse

Applications: WB, IHC

All Applications: WB:1:500~1:1000 IHC:1:50~1:200

Background: Heterogeneous nuclear ribonucleoprotein U-like protein 2, is a multifunctional protein and previous studies have implicated it in the modulation of p53 transcriptional activity, although this has been rather poorly understood. Results presented here demonstrate that hnRNPUL-1 represses p53 transcriptional activity and negatively regulates p21 levels. This is consistent with the depletion of hnRNPUL-1 leading to an increase in cells arrested in G1/S. Together these results confirm that hnRNPUL-1 acts as a p53 co-repressor with specific cellular targets.

Purification and Purity: The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: hnRNP UL2 polyclonal antibody detects endogenous levels of hnRNP UL2 protein.

Extra Notes: Western blot (WB) analysis of hnRNP UL2 polyclonal antibody at 1:500 dilution
LaneA:Jurkat whole cell lysate
LaneB:HepG2 whole cell lysate
LaneC:MEF whole cell lysate
LaneD:PC12 whole cell lysate

Bioworld Molecular Weight: ~ 90 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Heterogeneous nuclear ribonucleoprotein U-like protein 2; Scaffold-attachment factor A2; SAF-A2; HNRNPUL2; HNRPUL2

Immunogen: Synthetic peptide, corresponding to Human hnRNP UL2.

Conjugate: Unconjugated

Modification: Unmodified