HOME3 rabbit pAb - ES15689

HOME3 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES15689-50, ES15689-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors, inositol 1, 4, 5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation and trafficking of amyloid beta peptides. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009],

Source: Rabbit

Applications: WB

Dilution: WB 1: 500-2000

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized peptide derived from human HOME3 AA range: 243-293

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 9454

Human SWISS Prot NO: Q9NSC5

Subcellular Location: Cytoplasm. Cell junction, synapse, postsynaptic density. Cell junction, synapse. Postsynaptic density of neuronal cells.

Research Use Only