Product Description

Hox-D8 Polyclonal Antibody

Catalogue Numbers: BS5760-50, BS5760-100

Sizes: 50µl, 100µl

Alternative Name: Homeobox protein Hox-D8; Homeobox protein Hox-4E; Homeobox protein Hox-5.4; Name: HOXD8; HOX4E; Hox-5.4;

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P13378

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB ICC

All Applications: WB: 1:500~1:1000
ICC: 1:50~1:200

Background: The Hox proteins are a family of transcription factors that play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Hox proteins are involved in controlling axial patterning, leukemias and hereditary malformations. HoxD8 (homeobox D8), also known as HOX4E, is a 290 amino acid protein that localizes to the nucleus and contains one homeobox DNA-binding domain. One of several members of the homeobox superfamily, HoxD8 functions as a sequence-specific transcription factor that is important for the correct positioning of developing limb buds on the anterior-posterior axis.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Hox-D8 polyclonal antibody detects endogenous levels of Hox-D8 protein.

Bioworld Molecular Weight: ~ 32 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of Hox-D8 polyclonal antibody at 1:500 dilution
Lane 1: Hela cell lysate
Lane 2: Raw264.7 cell lysate
Lane 3: H9C2 cell lysate

Immunogen: Synthetic peptide, corresponding to the 245-290 of Human Hox-D8.

Conjugate: Unconjugated

Modification: Unmodified