Product Description

HOXA3 Mouse Monoclonal Antibody

Sizes: 25μl, 100μl

Catalogue Numbers: MB4042-25, MB4042-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Homeobox protein Hox-D9 (HOXD9) is a sequence-specific transcription factor that is part of a developmental regμlatory program that provides cells with specific positional identities on the anterior-posterior axis. HOXD9 is developmentally expressed in structures of either mesodermal or neuro-ectodermal origin, such as developing limbs, gonads, and the central nervous system (1-6). HOXD9 plays a critical role in regμlation of limb development, neuronal development, and development of mammary glands and gonads in many organisms (1-6). The HOXD9 gene promoter is found to be hypermethylated and silenced in mμltiple types of cancer, including breast cancer, melanoma brain metastases, and cholangiocarcinomas (7-9). In addition, HOXD9 expression is increased in other types of cancer, including human glioblastomas and astrocytomas, where expression appears to drive growth of the tumors (10).

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Mouse

Applications: WB

Alternate Names: Homeobox protein Hox-A3, Homeobox protein Hox-1E, HOXA3, HOX1E, 9606 NCBI, Homo sapiens (Human)

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: Human recombinant protein fragment corresponding to amino acids 40-276 of human HOXA3 (NP_109377) produced in E.coli.

Dilution: WB 1:500~2000

Purification: The antibody was affinity-purified from mouse ascites fluids or tissue cμlture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: IgG1

Molecular Weight: ~ 46 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O43365

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only