HP-1α Mouse Monoclonal Antibody (5E3) - RA11429

HP-1α Mouse Monoclonal Antibody (5E3)

Size: 50μL, 100μL

Catalogue Numbers: RA11429-50, RA11429-100

Citations, Manuals and MSDS Available upon request.

Background: chromobox 5 (CBX5) Homo sapiens This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Applications: IF/ICC; WB; IHC-p

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 23468

Protein MW (KDa): 22

SWISS: P45973

Source: Mouse

Research Use Only