HP-1γ Mouse Monoclonal Antibody (4F4) Sizes: 50μL, 100μL Catalogue Numbers: RA11434-50, RA11434-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: chromobox 3 (CBX3) Homo sapiens At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.[provided by RefSeq, Mar 2011], Reactivity: Human, Mouse, Rat Host: Mouse Applications: WB, IHC-p, IF(paraffin section) Alternate Names: Chromobox protein homolog 3 (HECH, Heterochromatin protein 1 homolog gamma, HP1 gamma, Modifier 2 protein) Clonality: Monoclonal Dilution: WB 1:500-2000, IHC-p 1:50-300 Storage: -20°C/1 year Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Human Gene ID: 11335 Protein Molecular Weight（KDa): 24 Molecular Weight: 24 Research Use Only