HP1β Monoclonal Antibody - RA11430

HP1β Monoclonal Antibody

Size: 50μL, 100μL

Catalogue Numbers: RA11430-50, RA11430-100

Citations, Manuals and MSDS Available upon request.

Background: chromobox 1 (CBX1) Homo sapiens This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008],

Condition: Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.

Storage Instructions: -20°C/1 year

Applications: WB

Species Cross-Reactivity: Human; Mouse; Rat; Bovine; Chicken; Dog; Pig

GeneID (Human): 10951

SWISS: P83916

Source: Mouse

Research Use Only