Product Description

HP1 gamma Polyclonal Antibody

Product: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16855-50, BZ16855-100

Swiss-Prot: Q13185

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-P, IP, FC

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20 FC: 1/50-1/100

Background: Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Calculated MW: 21 kDa; Observed MW: 24 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of HP1 gamma in HeLa lysates; NIH/3T3 lysates using HP1 gamma antibody.

Alternative Name: CBX3; Chromobox protein homolog 3; HECH; Heterochromatin protein 1 homolog gamma; HP1 gamma; Modifier 2 protein

Immunogen: A synthesized peptide derived from human HP1 gamma

Conjugate: Unconjugated

Modification: Unmodified