Product Description

HRT2 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA26060-50, RA26060-100

Citations, Manuals and MSDS Available upon request.

Background: hes related family bHLH transcription factor with YRPW motif 2 (HEY2) Homo sapiens This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH) -type transcription factors. The encoded protein forms homo- or hetero-dimers that localize to the nucleus and interact with a histone deacetylase complex to repress transcription. Expression of this gene is induced by the Notch signal transduction pathway. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternatively spliced transcript variants have been found, but their biological validity has not been determined. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Alternative Names: HEY2; BHLHB32; CHF1; GRL; HERP; HERP1; HRT2; Hairy/enhancer-of-split related with YRPW motif protein 2; Cardiovascular helix-loop-helix factor 1; hCHF1; Class B basic helix-loop-helix protein 32; bHLHb32; HES-related repressor protein 2; Ha

Applications: WB; IHC-p; IF (paraffin section) ; ELISA

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 23493

Protein MW (KDa): 36

SWISS: Q9UBP5

Source: Rabbit

Research Use Only