Product Description

HSC 70 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP04223-20, BT-AP04223-50, BT-AP04223-100

Citations, Manuals and MSDS Available upon request.

Background: HSPA8 encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. Heat shock cognate 71 kDa protein belongs to the latter group, which are also referred to as heat-shock cognate proteins. It functions as a chaperone, and binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Research Areas: Signal Transduction

Target Protein: HSPA8

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: HSC 70 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 70898

UniProt Accession: Human: P11142; Mouse: P63017; Rat: P63018

Synonyms: HSPA8; HSC70; HSP73; HSPA10; Heat shock cognate 71 kDa protein; Heat shock 70 kDa protein 8

GeneID: Human: 3312; Mouse: 15481; Rat: 24468

Research Use Only