HSL (phospho Ser855) rabbit pAb - ES6120

HSL (phospho Ser855) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES6120-50, ES6120-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene has a long and a short form, generated by use of alternative translational start codons. The long form is expressed in steroidogenic tissues such as testis, where it converts cholesteryl esters to free cholesterol for steroid hormone production. The short form is expressed in adipose tissue, among others, where it hydrolyzes stored triglycerides to free fatty acids. [provided by RefSeq, Jul 2008],

Alternate Name: LIPE; Hormone-sensitive lipase; HSL

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human HSL around the phosphorylation site of Ser855/554. AA range:520-569

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 81kD

Human Gene ID: 3991

Human SWISS Prot NO: Q05469

Subcellular Location: Cell membrane. Membrane, caveola. Cytoplasm, cytosol. Lipid droplet. Found in the high-density caveolae. Translocates to the cytoplasm from the caveolae upon insulin stimulation (PubMed:17026959). Phosphorylation by AMPK reduces its translocation towards the lipid droplets (By similarity).

Research Use Only