HSPA14 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS90673-50, BS90673-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q0VDF9(Human) Q99M31(Mouse) Q6AYB4(Rat)
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB, ICC/IF, IHC, IP,
All Applications: WB:1:1,000-1:2,000
ICC:1:50-1:200
IHC:1:50-1:200
Background: The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multi-protein complexes, the transportation of nascent poly-peptide chains across cellular membranes and the regulation of protein folding. HSPA14 (heat shock 70kDa protein 14), also known as HSP70-4 or HSP70L1, is a 509 amino acid novel HSP protein derived from human dendritic cells. Belonging to the heat shock protein 70 family, HSPA14 is thought to promote dendritic cell maturation. It is also suggested that HSPA14 stimulates secretion of the proinflammatory cytokines interleukin 12p70 (IL-12p70), IL-1β, TNFα, and the chemokines IP-10, MIP-1α, MIP-1β, and normal T cell expressed and secreted (RANTES).
Purification and Purity: ProA affinity purified
Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: HSPA14 polyclonal antibody detects endogenous levels of HSPA14 protein.
Bioworld Molecular Weight: 55 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of HSPA14 on different lysates using anti-HSPA14 antibody at 1/1,000 dilution.
Positive control:
Lane 1: K562
Lane 2: COS-1, ICC staining HSPA14 in 293 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Alternative Name: HSPA14, Heat shock 70 kDa protein 14, Heat shock 70kDa protein 14, Heat shock protein HSP60, Heat shock protein hsp70 related protein, HSP60, HSP70 4, HSP70 like protein 1, HSP70-like protein 1, HSP70L1, HSP7E, HSPA 14, HSPA14, MGC131990,
Immunogen: recombinant protein
Conjugate: Unconjugated
Modification: Unmodified