Product Description

HSPB2 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65896-50, BS65896-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of mμlti-protein complexes, transportation of nascent polypeptide chains across cellμlar membranes and regμlation of protein folding. HSPB2 (heat shock 27 kDa protein 2), also known as HSP 27 or MKBP, is a 182 amino acid protein that belongs to the heat shock protein family and is expressed preferentially in heart and skeletal muscle. Localized to mitochondria, HSPB2 functions as an ATP-dependent chaperone protein that plays a role in the refolding of denatured proteins and may also interact with the Actin cytoskeleton and prevent apoptotic cell death. HSPB2 is abundantly expressed in several cancer cell lines, suggesting that HSPB2 may be an important factor in tumor transformation and metastasis.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit

Host: Rabbit

Applications: IHC-P

Alternate Names: DMPK-binding protein, Heat shock 27kD protein 2, Heat shock 27kDa protein 2, Heat shock protein beta-2, Heat-shock protein beta-2, Hs.78846, HSP27, HspB2, HSPB2_HUMAN, LOH11CR1K, MGC133245, MKBP.

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human HSPB2:101-182/182

Dilution: IHC-P=1:100-500

Purification: affinity purified by Protein A

Specificity: HSPB2 Polyclonal Antibody detects endogenous levels of HSPB2 protein.

Molecular Weight: 20kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q16082

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only