HSPB8/HSP22 Monoclonal Antibody (2C3) - RA11468

HSPB8/HSP22 Monoclonal Antibody (2C3)

Size: 50μL, 100μL

Catalogue Numbers: RA11468-50, RA11468-100

Citations, Manuals and MSDS Available upon request.

Background: heat shock protein family B (small) member 8 (HSPB8) Homo sapiens The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Applications: WB

Species Cross-Reactivity: Human; Rat; Mouse

GeneID (Human): 26353

Protein MW (KDa): 22

SWISS: Q9UJY1

Source: Mouse

Research Use Only