Product Description

HTRA1 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-53300-60, E-AB-53300-120, E-AB-53300-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: HTRA1

Target Synonym: ARMD7; CARASIL; High-temperature requirement A serine peptidase 1; HtrA; HtrA serine peptidase 1; HTRA1; HTRA1; IGFBP5 protease; L56; ORF480; Protease serine 11 (IGF binding); protease serine 11; PRSS11 ; Serine protease 11; Serine protease HTRA1; Serine protease HTRA1 precursor

Research Areas: Cancer, Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB, IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q92743

Background: This gene encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7.

Concentration: 0.9 mg/mL

Immunogen: Synthetic peptide of human HTRA1

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000

Calculated MW: 51 kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only