HtrA2 (8G11) Monoclonal Antibody-MB3048

HtrA2 (8G11) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB3048-50, MB3048-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: O43464

Host: Mouse

Reactivity: Human

Applications: WB, IP,

All Applications: WB: 1/500-1/1000 IP: 1/20

Background: High temperature requirement protein A2 (HtrA2)/Omi is a serine protease with homology to the E. coli HtrA protein (DegP) and is thought to be involved in apoptosis and stress-induced degradation of misfolded proteins. While HtrA2 was orignally identified to be present in either the nucleus or endoplasmic reticulum, subsequent studies have shown that it localizes in mitochondria and is released during apoptosis.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG1

Bioworld Molecular Weight: Calculated MW: 49 kDa; Observed MW: 37 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of HtrA2/Omi in 293T lysates using HtrA2/Omi antibody., Immunoprecipitation analysis of HtrA2 in Hela lysates using HtrA2/Omi antibody.

Alternative Name: High temperature requirement protein A2; HTRA 2; HtrA like serine protease; HtrA serine peptidase 2; HtrA; E. coli; homolog of; 2; HtrA2; HTRA2_HUMAN; mitochondrial; Omi stress regulated endoprotease; Omi stress-regulated endoprotease; PARK 13; PARK13; Protease serine 25; PRSS 25; PRSS25; Serine protease 25; Serine protease HTRA2; Serine protease HTRA2 mitochondrial; Serine protease htra2 mitochondrial precursor; Serine protease omi; Serine proteinase OMI.

Immunogen: Recombinant human HtrA2/Omi protein.

Conjugate: Unconjugated

Modification: Unmodified