HtrA2 Polyclonal Antibody - BT-AP04279

HtrA2 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP04279-20, BT-AP04279-50, BT-AP04279-100

Citations, Manuals and MSDS Available upon request.

Background: HTRA2 encodes a serine protease. The HtrA serine peptidase 2 has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.

Research Areas: Neuroscience

Target Protein: HTRA2

Applications: WB, IHC-p, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: HtrA2 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 48841

UniProt Accession: Human: O43464; Mouse: Q9JIY5

Synonyms: HTRA2; OMI; PRSS25; Serine protease HTRA2; mitochondrial; High temperature requirement protein A2; HtrA2; Omi stress-regulated endoprotease; Serine protease 25; Serine proteinase OMI

GeneID: Human: 27429; Mouse: 64704

Research Use Only