Product Description

HTRA2 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-90984-60, E-AB-90984-120, E-AB-90984-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: HTRA2

Target Synonym: HTRA2; MGCA8; OMI; PARK13; PRSS25

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB, IP

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: O43464

Background: This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human HTRA2

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IP 1:50-1:100

Calculated MW: 38kDa/39kDa/46kDa/48kDa

Observed MW: 36kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only