Product Description

Human CD28 (3G5E) Monoclonal Antibody

Catalogue Numbers:EP0028-50, EP0028-100

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P10747

Host: Mouse

Reactivity: Human

Applications: FCM IHC-Fr IP T cell Co-stimulation

All Applications: Flow Cytometry (5 µg/ml)
Frozen Sections (User-optimized)
Immunoprecipitation (User-optimized)
T cell Co-stimulation (User-optimized)

Background: Human CD28 is an important co-stimulatory molecule found on all CD4+ T cells and ~50% of CD8+ T cells. T cell activities attributed to CD28 include prevention of anergy, induction of cytokine gene transcription, stabilization of cytokine mRNA, and activation of CD8+ cytotoxic T lymphocytes. The ligands for CD28, known as CD80 (B7-1) and CD86 (B7-2), are monomeric transmembrane glycoproteins.

Purification and Purity: Protein A purified mouse monoclonal antibody, >95% immunoglobulin by SDS-PAGE

Storage and Stability: Following initial use, aliquot and freeze (-20°C) for long-term storage. Avoid freeze/thaw cycles.

Bioworld Molecular Weight: ~ 25 kDa

Specificity: Recognizes the CD28 protein.

Note: For research use only, not for use in diagnostic procedure.
Alternative Name: T-cell-specific surface glycoprotein CD28; TP44; CD28

Immunogen: Human CD28 Ig fusion protein and HPB-MLT human tumor cells.

Conjugate: Unconjugated

Modification: Unmodified