HXB8 Polyclonal Antibody - BT-AP10241

HXB8 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP10241-20, BT-AP10241-50, BT-AP10241-100

Citations, Manuals and MSDS Available upon request.

Background: This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.

Research Areas: Cancer; Developmental biology; Epigenetics and nuclear signaling; Stem cells

Target Protein: HOXB8

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Homeobox protein Hox-B8

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P17481; Mouse: P09632; Rat: P18863

Synonyms: Homeobox protein Hox-B8;Homeobox protein Hox-2.4;Homeobox protein Hox-2D

GeneID: Human: 3218

Research Use Only