Hydroxyl-Histone H2A (Tyr39) Monoclonal Antibody-MB12330

Hydroxyl-Histone H2A (Tyr39) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB12330-50, MB12330-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P04908

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, IHC-P

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100

Background: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 14 kDa; Observed MW: 14 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Hydroxyl-Histone H2A in 3T3 lysates using Hydroxyl-Histone H2A antibody., Western blot analysis of Hydroxyl-Histone H2A in Hela, A549, HL-60 lysates using Hydroxyl-Histone H2A antibody.Observed band size:14kDa., Immunohistochemistry analysis of paraffin-embedded Human lung cancer using Hydroxyl-Histone H2A antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Alternative Name: H2A.1; H2A/c; H2A1; H2AFC:; H2AFD; H2AFI; H2AFN; H2AFP; HIST1H2AG; HIST1H2AI; HIST1H2AK; HIST1H2AL; HIST1H2AM; histone cluster 1; H2ai; Histone H2A type 1; Histone H2A/p

Immunogen: A synthesized peptide derived from human Histone H2A (hydroxyl Y39)

Conjugate: Unconjugated

Modification: Hydroxylated