I Kappa B Beta Monoclonal Antibody (8D11) - BT-MCA0791

I Kappa B Beta Monoclonal Antibody (8D11)

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-MCA0791-20, BT-MCA0791-50, BT-MCA0791-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.

Research Areas: Signal transduction; Immunology; Epigenetics and nuclear signaling

Target Protein: NFKBIB

Applications: IHC-p, IF

Reactivity: Human,Rat,Mouse

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: NF-kappa-B inhibitor beta

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q15653; Mouse: Q60778; Rat: Q9JIA3

Synonyms: NFKBIB; IKBB; TRIP9; NF-kappa-B inhibitor beta; NF-kappa-BIB; I-kappa-B-beta; IkB-B; IkB-beta; IkappaBbeta; Thyroid receptor-interacting protein 9; TR-interacting protein 9; TRIP-9

GeneID: Human: 4793

Research Use Only