Product Description

I23O1 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA32725-50, RA32725-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: indoleamine 2, 3-dioxygenase 1 (IDO1) Homo sapiens This gene encodes indoleamine 2, 3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 44

Protein Molecular Weight (kDa): 44

Storage: -20°C/1 year

Human Gene ID: 3620

Human SwissProt Number: P14902

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only