IBA1 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS90680-50, BS90680-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: P55008(Human) O70200(Mouse)
Host: Rabbit
Reactivity: Human, Mouse
Applications: IHC
All Applications: IHC:1:50-1:200
Background: Ionized calcium-binding adapter molecule 1 (Iba1), also known as allograft inflammatory factor-1 (AIF-1), is a 147 amino acid cytoplasmic, calcium-binding protein that is thought to play a role in macrophage activation and function. Iba1, containing two EF domains, is induced by cytokines and interferons. In an unstimulated state, Iba1 colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding Iba1 maps to chromosome 6p21.33 and resides in the tumor necrosis factor (TNF) cluster of genes located in the region represented by the human major histocompatibility complex (MHC).
Purification and Purity: Peptide affinity purified
Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: IBA1 polyclonal antibody detects endogenous levels of IBA1 protein.
Bioworld Molecular Weight: 17/10/15 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Iba1 antibody. Counter stained with hematoxylin., Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-Iba1 antibody. Counter stained with hematoxylin.
Alternative Name: AIF-1, AIF1, G1, IBA1, AIF 1, AIF-1, Aif1, AIF1 protein, AIF1, Allograft inflammatory factor 1, Allograft inflammatory factor 1 splice variant G, allograft inflammatory factor-1 splice variant Hara-1, balloon angioplasty responsive transcription, BART 1, G1, G1 putative splice variant of allograft inflamatory factor 1, IBA 1, IBA1, interferon gamma responsive transcript, Interferon responsive transcript 1, interferon responsive transcript factor 1, Ionized calcium binding adapter molecule 1, Ionized calcium-binding adapter molecule 1, ionized calcium-binding adapter molecule, IRT 1, IRT1, Microglia response factor, MRF1, Protein g1,
Immunogen: Peptide
Conjugate: Unconjugated
Modification: Unmodified