IBTK Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA32730-50, RA32730-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: inhibitor of Bruton tyrosine kinase (IBTK) Homo sapiens Bruton tyrosine kinase (BTK) is a protein tyrosine kinase that is expressed in B cells, macrophages, and neutrophils. The protein encoded by this gene binds to BTK and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription. This gene has a pseudogene on chromosome 18. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014], Reactivity: Human, Rat, Mouse Host: Rabbit Applications: WB, ELISA Clonality: Polyclonal Dilution: WB 1:500-2000 ELISA 1:5000-20000 Molecular Weight: 148 Protein Molecular Weight (kDa): 148 Storage: -20°C/1 year Human Gene ID: 25998 Human SwissProt Number: Q9P2D0 Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. Research Use Only