IBTK Polyclonal Antibody - RA32730

IBTK Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA32730-50, RA32730-100 Citations, Manuals and MSDS Available upon request. Background: inhibitor of Bruton tyrosine kinase (IBTK) Homo sapiens Bruton tyrosine kinase (BTK) is a protein tyrosine kinase that is expressed in B cells, macrophages, and neutrophils. The protein encoded by this gene binds to BTK and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription. This gene has a pseudogene on chromosome 18. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014], Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. Storage Instructions: -20°C/1 year Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000 Applications: WB; ELISA Species Cross-Reactivity: Human; Rat; Mouse GeneID (Human): 25998 Protein MW (KDa): 148 SWISS: Q9P2D0 Source: Rabbit Research Use Only