Product Description

ICK(Phospho-Tyr159)Polyclonal Antibody

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Sizes: 50µl, 100µl

Catalogue Numbers: BS65329-50, BS65329-100

Swiss-Prot: Q9UPZ9

Host: Rabbit

ICK(Phospho-Tyr159)Polyclonal Antibody-BS65329

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat

Applications: WB, ELISA

All Applications: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Background: intestinal cell kinase(ICK) Homo sapiens Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. This gene encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. The protein localizes to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. Alternative splicing has been observed at this locus and two variants, encoding the same isoform, have been identified. [provided by RefSeq, Jul 2008],

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity: Phospho-Intestinal Cell Kinase (Y159) Polyclonal Antibody detects endogenous levels of Intestinal Cell Kinase protein only when phosphorylated at Y159.

Bioworld Molecular Weight: ~ 71 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western Blot analysis of 3T3 cells using Phospho-Intestinal Cell Kinase (Y159) Polyclonal Antibody, Western blot analysis ofLysates from NIH/3T3 cells treated with starved 24h, using ICK (Phospho-Tyr159) Antibody. The lane on the right is blocked with the phospho peptide.

Alternative Name: ICK; KIAA0936; Serine/threonine-protein kinase ICK; Intestinal cell kinase; hICK; Laryngeal cancer kinase 2; LCK2; MAK-related kinase; MRK

Immunogen: The antiserum was produced against synthesized peptide derived from human ICK around the phosphorylation site of Tyr159. AA range:125-174

Modification: Phosphorylation

Conjugate: Unconjugated