IDE/Insulin Degrading Enzyme Mouse mAb - EM1083

IDE/Insulin Degrading Enzyme Mouse mAb

Sizes: 50μL, 100μL

Catalogue Numbers: EM1083-50, EM1083-100

Citations, Manuals and MSDS Available upon request.

Background: Insulin Degrading Enzyme (IDE) is a large zinc-binding protease of the M16A metalloprotease subfamily known to cleave multiple short polypeptides that vary considerably in sequence. IDE was first identified by its ability to degrade the B chain of the hormone insulin. This activity was observed over fifty years ago, though the enzyme specifically responsible for B chain cleavage was identified more recently.

Alternate Name: Abeta degrading protease, insulin degrading enzyme, Insulin protease, Insulinase, INSULYSIN

Source: Mouse

Applications: WB, IHC

Dilution: WB 1:1, 000 IHC 1:200

Reactivity: Human

Immunogen: Synthetic Peptide

Storage and Stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality: Monoclonal

Isotype: IgG1

Concentration: 1mg/mL

Observed Band (KD): 118kDa

Human Gene ID: 3416

Human SWISS Prot NO: P14735

Subcellular Location: Cell membrane,  Cytoplasm,  Membrane,  Secreted

Research Use Only