IDH1 Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB10264-50, MB10264-100
Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Swiss-Prot: O75874
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB, IHC-P, IP,
All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20
Background: Genetic variations are associated with cartilaginous tumors such as enchondroma or chondrosarcoma. Mutations of Arg-132 to Cys, Gly or His abolish the conversion of isocitrate to alpha-ketoglutarate. Instead, alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IgG
Bioworld Molecular Weight: Calculated MW: 47 kDa; Observed MW: 47 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of IDH1 in rat Brain, C6, 3T3, Hela lysates using IDH1 antibody., Immunohistochemistry analysis of paraffin-embedded Human Cholangiocarcinoma using Isocitrate dehydrogenase antibody. High-pressure and temperature Sodium Citrate pH 6. 0 was used for antigen retrieval.
Alternative Name: IDH1; PICD; Isocitrate dehydrogenase [NADP] cytoplasmic; IDH; Cytosolic NADP-isocitrate dehydrogenase; IDP; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase
Immunogen: A synthetic peptide of human Isocitrate dehydrogenase
Conjugate: Unconjugated
Modification: Unmodified