IDH3B rabbit pAb - ES11913

IDH3B rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES11913-50, ES11913-100

Citations, Manuals and MSDS Available upon request.

Background: isocitrate dehydrogenase 3 (NAD (+)) beta (IDH3B) Homo sapiens Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD (+) as the electron acceptor and the other NADP (+). Five isocitrate dehydrogenases have been reported: three NAD (+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP (+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD (+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the beta subunit of one isozyme of NAD (+)-dependent isocitrate dehydrogenase. Multiple alternatively spliced transcript va

Source: Rabbit

Applications: WB; ELISA

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Reactivity: Human; Rat

Immunogen: Synthesized peptide derived from part region of human protein

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 42kD

Human Gene ID: 3420

Human SWISS Prot NO: O43837

Subcellular Location: Mitochondrion.

Research Use Only