Product Description

IDO 2 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BZ16211-50, BZ16211-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: INDOL1 is also known as IDO2 (indoleamine 2, 3-dioxygenase 2) and is a 407 amino acid protein that is expressed in various tissues, including liver, small inTine, spleen, placenta, thymus, lung, brain, kidney, colon and dendritic cells. INDOL1 is selectively inhibited by D-1MT (1-methyl-d-tryptophan), which also inhibits IDO (indoleamine 2, 3-dioxygenase) and is significant because IDO expression causes suppression of T cell responses to tumors in dendritic cells. The inhibition of INDOL1 by D-1MT suggests a common function in immunomodμlation. In the human INDOL1 gene, two single nucleotide polymorphisms have been detected which abolish the enzymatic function of INDOL1.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB, ELISA

Alternate Names: IDO2, INDOL1, Indoleamine 2, 3-dioxygenase 2, IDO-2, Indoleamine 2, 3-dioxygenase-like protein 1, Indoleamine-pyrrole 2, 3-dioxygenase-like protein 1

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human IDO2. AA range:101-150

Dilution: WB: 1/500-1/1000 ELISA: 1/10000

Purification: Affinity Purified

Specificity: IgG

Molecular Weight: Calcμlated MW: 47 kDa, Observed MW: 47 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q6ZQW0

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Research Use Only