Product Description

IDO1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS6639-50, BS6639-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes indoleamine 2, 3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on mμltiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregμlation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modμlates T-cell behavior by its peri-cellμlar catabolization of the essential amino acid tryptophan.

Category: Primary Antibody

Reactivity: Human, Rat

Host: Rabbit

Applications: WB, IF/ICC

Alternate Names: IDO1, IDO, IDO-1, INDO, indoleamine 2

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fusion protein of human IDO1(NP_002155.1).

Dilution: WB, 1:500 - 1:2000 IF/ICC, 1:50 - 1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Polyclonal Antibodies

Molecular Weight: 40KDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P14902

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only