IDO1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A1614-20, A1614-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes indoleamine 2, 3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.
Category: Polyclonal Antibodies
Applications: WB, IF/ICC, ELISA
Cross-reactivity: Human, Rat
Protein Weight: 45kDa
Observed Molecular Weight: 43kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 3620
SWISS: P14902
Alternate Names: IDO; INDO; IDO-1; IDO1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:100 - 1:500 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Signal Transduction, Endocrine Metabolism, Amino acid metabolism, Immunology Inflammation, Cardiovascular.
NCBI Alias: IDO1
Research Use Only