IDO2 Polyclonal Antibody - E-AB-18375

IDO2 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-18375-60, E-AB-18375-120, E-AB-18375-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: IDO2

Target Synonym: 3-dioxygenase 2; 3-dioxygenase-like protein 1; EC 1.13.11.; I23O2; IDO 2; IDO-2; Ido2; INDOL 1; Indoleamine 2; Indoleamine 2; 3 dioxygenase 2; Indoleamine 2; 3 dioxygenase like 1 protein; Indoleamine 2; 3 dioxygenase like protein 1; Indoleamine pyrrole 2; 3 dioxygenase like 1; Indoleamine pyrrole 2; 3 dioxygenase like protein 1; Indoleamine-pyrrole 2

Research Areas: Metabolism, Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: WB, IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q6ZQW0

Background: INDOL1 is also known as IDO2 (indoleamine 2, 3-dioxygenase 2) and is a 407 amino acid protein that is expressed in various tissues, including liver, small intestine, spleen, placenta, thymus, lung, brain, kidney, colon and dendritic cells. INDOL1 is selectively inhibited by D-1MT (1-methyl-d-tryptophan), which also inhibits IDO (indoleamine 2, 3-dioxygenase) and is significant because IDO expression causes suppression of T cell responses to tumors in dendritic cells. The inhibition of INDOL1 by D-1MT suggests a common function in immunomodulation. In the human INDOL1 gene, two single nucleotide polymorphisms have been detected which abolish the enzymatic function of INDOL1.

Concentration: 1 mg/mL

Immunogen: Full length fusion protein

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000

Calculated MW: 45 kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only