IDS Polyclonal Antibody - BT-AP08601

IDS Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP08601-20, BT-AP08601-50, BT-AP08601-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the sulfatase family of proteins. The encoded preproprotein is proteolytically processed to generate two polypeptide chains. This enzyme is involved in the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this gene are associated with the X-linked lysosomal storage disease mucopolysaccharidosis type II| also known as Hunter syndrome. Alternative splicing results in multiple transcript variants| at least one of which encodes a preproprotein that is proteolytically processed.

Research Areas: Cell biology; Tags and cell markers

Target Protein: IDS

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Iduronate 2-sulfatase

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P22304; Mouse: Q08890

Synonyms: Iduronate 2-sulfatase;EC 3.1.6.13;Alpha-L-iduronate sulfate sulfatase;Idursulfase [Cleaved into: Iduronate 2-sulfatase 42 kDa chain; Iduronate 2-sulfatase 14 kDa chain]

GeneID: Human: 3423

Research Use Only