IF2M Polyclonal Antibody - BT-AP01982

IF2M Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP01982-20, BT-AP01982-50, BT-AP01982-100

Citations, Manuals and MSDS Available upon request.

Background: During the initiation of protein biosynthesis| initiation factor-2 (IF-2) promotes the binding of the initiator tRNA to the small subunit of the ribosome in a GTP-dependent manner. Prokaryotic IF-2 is a single polypeptide| while eukaryotic cytoplasmic IF-2 (eIF-2) is a trimeric protein. Bovine liver mitochondria contain IF-2(mt)| an 85-kD monomeric protein that is equivalent to prokaryotic IF-2. The predicted 727-amino acid human protein contains a 29-amino acid presequence. Human IF-2(mt) shares 32 to 38% amino acid sequence identity with yeast IF-2(mt) and several prokaryotic IF-2s| with the greatest degree of conservation in the G domains of the proteins.

Research Areas: Epigenetics and nuclear signaling

Target Protein: MTIF2

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Translation initiation factor IF-2, mitochondrial

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P46199; Mouse: Q91YJ5

Synonyms: Translation initiation factor IF-2; mitochondrial;IF-2;Mt;IF-2Mt;IF2;mt

GeneID: Human: 4528

Research Use Only