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View abinScience ELISA, antibody, protein collection

Ifabotuzumab ELISA Kit - DB681018

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Ifabotuzumab ELISA Kit

Size: 96T

Catalogue Number: DB681018-96

Citations, Manuals and MSDS Available upon request.

Stability and Storage: The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.

Detection Method: Colorimetric

Sample Type: Plasma, Serum

Assay Type: Quantitative

Sensitivity: 0.156 μg/ml

Range: 0.31-5 μg/mL

Recovery: 80-120%

Background: Ifabotuzumab (formerly KB004) is a first-in-class therapeutic non-fucosylated IgG1 (human f-allotype) monoclonal antibody being developed by Humanigen (formerly KaloBios Pharmaceuticals) for the treatment of cancer. The drug was licensed from the Ludwig Institute for Cancer Research. The molecule contains a human antibody constant region with V-regions that are 92% identical to human germ-line sequences. Ifabotuzumab targets the ephrin type-A receptor 3 (EphA3) tyrosine kinase. In non-clinical studies, Ifabotuzumab demonstrated potent ex-vivo cell killing of EphA3+ tumor cells obtained from patients with hematologic malignancies.

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For Research Use Only.