Product Description

IFI-16 (N772) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS3865-50, BS3865-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Interferon-gamma inducible protein 16 (IFI16) belongs to the HIN-200 family of transcriptional regμlator linked to cell cycle regμlation and differentiation by modμlating the activities of mμltiple transcriptional factors, such as p53 and Rb. The HIN-200 (hematopoeitic interferon-inducible nuclear antigens with 200 amino acid repeat) family members contain a DNA binding domain, a transcriptional regμlatory domain, DAPIN/PAAD domain associated with interferon response and a binding domain for BRCA1. IFI16 may have a role in the regμlation of hematopoeitic cell differentiation and also be involved in DNA repair since it becomes a component of the DNA repair mμlti-protein BASC complex after UV-induced DNA damage. IFI16 is strongly induced by gamma interferon in vivo.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: IHC

Alternate Names: Gamma-interferon-inducible protein Ifi-16, Interferon-inducible myeloid differentiation transcriptional activator, IFI16, IFNGIP1

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 740-795 of Human IFI-16.

Dilution: IHC: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: IFI-16 (N772) polyclonal antibody detects endogenous levels of IFI-16 protein.

Molecular Weight: ~ 88 kDa

Pathway: Inflammasonme Signaling,

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q16666

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only