IFIH1 Polyclonal Antibody-BS2355

IFIH1 Polyclonal Antibody

Catalogue Numbers: BS2355-50, BS2355-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q9BYX4

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB

All Applications: WB: 1:500~1:1000

Background: IFIH1 (interferon induced with helicase C domain 1), also known as MDA5 (melanoma differentiation-associated protein 5), is one of a family of intracellular proteins known to recognise viral RNA and mediate the innate immune response. IFIH1 is causal in type 1 diabetes based on the protective associations of four rare variants, where the derived alleles are predicted to reduce gene expression or function.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IFIH1 polyclonal antibody detects endogenous levels of IFIH1 protein.

Extra Notes: Western blot (WB) analysis of IFIH1 polyclonal antibody at 1:500 dilution
Lane1:DLD whole cell lysate(40ug)
Lane2:Panc1 whole cell lysate(40ug)
Lane3:HCT116 whole cell lysate(40ug)
Lane4:PC3 whole cell lysate(40ug)
Lane5:CT26 whole cell lysate(40ug)

Bioworld Molecular Weight: ~ 135 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Interferon-induced helicase C domain-containing protein 1; Clinically amyopathic dermatomyositis autoantigen 140 kDa; CADM-140 autoantigen; Helicase with 2 CARD domains; Helicard; Interferon-induced with helicase C domain protein 1; Melanoma differentiation-associated protein 5; MDA-5; Murabutide down-regulated protein; RIG-I-like receptor 2; RLR-2; RNA helicase-DEAD box protein 116; IFIH1; MDA5; RH116

Immunogen: Synthetic peptide, corresponding Human IFIH1.

Conjugate: Unconjugated

Modification: Unmodified