Product Description

IFN alpha 1 Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB66766-50, MB66766-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The genes encoding type I interferons (IFNs), which include 14 IFN-a genes, one IFN-β gene, one IFN-w (also known as IFN-a II1) gene, and a number of IFN-w pseudogenes, are clustered on human chromosome 9. Interferon-a and -β are cytokines that are widely known to induce potent antiviral activity. They exert a variety of other biological effects, including antitumor and immunomodμlatory activities and are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. IFN-w is antigenically different from human IFN-a, IFN-β or IFN-g, but is a component of natural mixtures of IFN species produced by virus-induced leukocytes or Burkitt’s lymphoma cells. The type I interferon receptor (IFN-aR) interacts with IFN-a, IFN-β and IFN-w, and seems to be a mμltisubunit receptor.

Category: Primary Antibody

Reactivity: Human

Host: Mouse

Applications: WB

Alternate Names: Interferon alpha-1/13, IFN-alpha-1/13, Interferon alpha-D, LeIF D

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fusion protein of human IFN alpha 1. The exact sequence is proprietary.

Dilution: WB (1/500 - 1/1000)

Purification: This antibody is purified through a protein G column.

Specificity: Recognizes endogenous levels of IFN alpha 1 protein.

Molecular Weight: ~ 17 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P01562

Product: Mouse IgG1 kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Research Use Only