Product Description

IFN beta Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS62219-50, BS62219-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The genes encoding type I interferons (IFNs), which include 14 IFN-α genes, one IFN-β gene, one IFN-w (also known as IFN-α II1) gene, and a number of IFN-w pseudogenes, are clustered on human chromosome 9. Interferons-α and -β are cytokines that are widely known to induce potent antiviral activity. IFN-α and -β exert a variety of other biological effects, including antitumor and immunomodμlatory activities and are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. IFN-w is antigenically different from human IFN-α, IFN-β or IFN-γ, but is a component of natural mixtures of IFN species produced by virus-induced leukocytes or Burkitt's lymphoma cells. The type I interferon receptor (IFN-αR) interacts with IFN-α, IFN-β and IFN-w, and seems to be a mμltisubunit receptor.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC

Alternate Names: Interferon beta, Interferon β, IFN-beta, IFN-β, IFNβ, Fibroblast interferon, IFB, IFNB

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to Human IFN beta.

Dilution: WB:1:500~1:1000 IHC:1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: IFN beta  polyclonal antibody detects endogenous levels of IFN beta protein.

Molecular Weight: ~ 22 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P01574

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only