Product Description

IFN-beta Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP02022-20, BT-AP02022-50, BT-AP02022-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a cytokine that belongs to the interferon family of signaling proteins| which are released as part of the innate immune response to pathogens. The protein encoded by this gene belongs to the type I class of interferons| which are important for defense against viral infections. In addition| type I interferons are involved in cell differentiation and anti-tumor defenses. Following secretion in response to a pathogen| type I interferons bind a homologous receptor complex and induce transcription of genes such as those encoding inflammatory cytokines and chemokines. Overactivation of type I interferon secretion is linked to autoimmune diseases. Mice deficient for this gene display several phenotypes including defects in B cell maturation and increased susceptibility to viral infection.

Research Areas: Cancer; Immunology; Cardiovascular; Cell biology; Signal transduction

Target Protein: IFNB1

Applications: IHC-p, IF, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Interferon beta

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P01574; Mouse: P01575

Synonyms: Interferon beta (IFN-beta;Fibroblast interferon); Interferon beta; IFN-beta; Fibroblast interferon)

GeneID: Human: 3456; Mouse: 15977

Research Use Only