IFN-R1 Polyclonal Antibody-BS7140

IFN-R1 Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Sizes: 50µl, 100µl

Catalogue Numbers: BS7140-50, BS7140-100

Swiss-Prot: P17181

Host: Rabbit

IFN-R1 Polyclonal Antibody-BS7140

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

All Applications: WB: 1:500~1:2000
IHC: 1:50~1:200

Background: The type I interferons, IFN-α and IFN-β, are a group of structurally and functionally related proteins that are induced by either viruses or double-stranded RNA and are defined by their ability to confer an antiviral state in cells. IFN-α and IFN-β appear to compete with one another for binding to a common cell surface receptor, while immune IFN (IFN-γ) binds to a distinct receptor. This distinct receptor, IFN-αR, is only weakly responsive to type I interferons, in contrast to IFN-α/βR, which binds to and responds effectively to IFN-β and to several of the IFN-α subtypes. IFN-α/βR is expressed as two alternatively spliced transcripts, designated IFN-α/βRα (IFN-α/βR1) and IFN-α/βRβ (IFN- α/βR2), both of which are involved in signal transduction and ligand binding.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: IFN-R1 polyclonal antibody detects endogenous levels of IFN-R1 protein.

Bioworld Molecular Weight: ~ 64 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of IFN-R1 polyclonal antibody, Immunohistochemistry (IHC) analysis of IFN-R1 polyclonal antibody in paraffin-embedded Human Liver Cancer tissue.

Alternative Name: Interferon alpha/beta receptor 1; IFN-R-1; IFN-alpha/beta receptor 1; Cytokine receptor class-II member 1; Cytokine receptor family 2 member 1; CRF2-1; Type I interferon receptor 1; IFNAR1; IFNAR; IFNR1; IFN R1; IFN-α/βRα; IFN-α/βR1; IFN α/βRα; IFNα/βR1; IFNα/β-Rα; IFNα/β R1;

Immunogen: Recombinant full length Human IFN-R1.

Modification: Unmodified

Conjugate: Unconjugated