IFN-R1 Rabbit Monoclonal Antibody-BS9863M

IFN-R1 Rabbit Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS9863M-50, BS9863M-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P17181

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC FC

All Applications: WB: 1:1000-1:2000
IHC: 1:50-1:200
FC: 1:50-1:100

Background: The type I interferons, IFN-α and IFN-β, are a group of structurally and functionally related proteins that are induced by either viruses or double-stranded RNA and are defined by their ability to confer an antiviral state in cells. IFN-α and IFN-β appear to compete with one another for binding to a common cell surface receptor, while immune IFN (IFN-γ) binds to a distinct receptor. This distinct receptor, IFN-αR, is only weakly responsive to type I interferons, in contrast to IFN-α/βR, which binds to and responds effectively to IFN-β and to several of the IFN-α subtypes. IFN-α/βR is expressed as two alternatively spliced transcripts, designated IFN-α/βRα (IFN-α/βR1) and IFN-α/βRβ (IFN- α/βR2), both of which are involved in signal transduction and ligand binding.

Purification and Purity: Protein A affinity purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: This antibody detects endogenous levels of IFN-R1 and does not cross-react with related proteins.

Bioworld Molecular Weight: ~ 50 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-IFN-R1 antibody. Counter stained with hematoxylin, Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-IFN-R1 antibody. Counter stained with hematoxylin., Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-IFN-R1 antibody. Counter stained with hematoxylin

Alternative Name: Interferon alpha/beta receptor 1; IFN-R-1; IFN-alpha/beta receptor 1; Cytokine receptor class-II member 1; Cytokine receptor family 2 member 1; CRF2-1; Type I interferon receptor 1; IFNAR1; IFNAR; IFNR1; IFN R1; IFN-α/βRα; IFN-α/βR1; IFN α/βRα; IFNα/βR1; IFNα/β-Rα; IFNα/β R1;

Immunogen: Recombinant antibody.

Conjugate: Unconjugated

Modification: Unmodified