Ifna1 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS90686-50, BS90686-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: P01562(Human) P01572(Mouse) P05011(Rat)
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB, ICC IHC FC
All Applications: WB:1:500
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100
Background: The genes encoding type I interferons (IFNs), which include 14 IFN-α genes (two of which are IFN-α1 and IFN-α13), one IFN-β gene, one IFN-w (also known as IFN-α II1) gene and a number of IFN-w pseudogenes, are clustered on human chromosome 9. IFN-α and -β are cytokines that are widely known to induce potent antiviral activity. They exert a variety of other biological effects, including antitumor and immunomodulatory activities and are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. IFN-w is antigenically different from human IFN-α, IFN-β or IFN-γ, but is a component of natural mixtures of IFN species produced by virus-induced leukocytes or Burkitt's lymphoma cells. The type I interferon receptor (IFN-αR) interacts with IFN-α, IFN-β and IFN-w, and seems to be a multisubunit receptor.
Purification and Purity: Peptide affinity purified
Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: Ifna1 polyclonal antibody detects endogenous levels of Ifna1 protein.
Bioworld Molecular Weight: 22 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of IFNA1 on mouse liver tissue lysate using anti-IFNA1 antibody at 1/100 dilution., ICC staining IFNA1 in N2A cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Alternative Name: IFN-alpha-1/13, LeIF D, IFNA1, IFNA13, IFN-alpha-14, IFN14, IFNA14, Interferon alpha 14, Interferon alpha H, Interferon alpha-14, Interferon alpha-H, Interferon lambda-2-H, Interferon lambda2H, LeIF H, LeIFH, MGC125756, MGC125757,
Immunogen: Peptide
Conjugate: Unconjugated
Modification: Unmodified